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TAU PROTEIN


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Neuroimmunology: Tau protein (also referred to as β transferrin and asialo-transferrin) is present in cerebrospinal fluid (CSF) and this is used as a marker for the identification of CSF leakage from the nose or the ear or the eyes or from the head or neck wound after an injury.

An example of positive Tau protein.

 + (anode)Blot: Positive Tau protein

 

 

 


The blot above shows positive identification of CSF in nasal fluid. In tracks 3, 4, and 5 there are two bands, in the same position as the control CSF (track 1).

An example of negative Tau protein.

 +(anode)Blot: Negative Tau protein         

 

 

 


This nasal fluid does not contain CSF as it resembles the serum control (track 2).


Key: 1 = control CSF, 2 = control serum, 3 = neat nasal fluid, 4 = 1/5 diluted nasal fluid and 5 = 1/10 diluted nasal fluid

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