Adrenal antibody

Adrenal antibody


ADRENAL ANTIBODY

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Adrenal antibody

Antigens: P450c17 (~57KDa), P450scc (~60KDa) and P450c21 (~56KDa). The ovary and the testis share the same antigen as the adrenal gland.

Disease: Rare autoimmune disease leading to adrenocorticol deficiency. Positive in 60-70% of patients with Addison's disease. Also found in cases of ovarian failure and autoimmune polyglandular disease.

The adrenal antibody is direct to the cell cytoplasm of the granulosa and fasciculata layer.

Email: A.R.Karim@bham.ac.uk
Neuroimmunology, The Medical School, University of Birmingham, Edgbaston, Birmingham, B15 2TT, England, U.K. Telephone UK 0121-415-8797,

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